Molecular characterization of drug-resistant Mycobacterium tuberculosis isolates circulating in China by multilocus PCR and electrospray ionization mass spectrometry.

نویسندگان

  • Feifei Wang
  • Christian Massire
  • Haijing Li
  • Lendell L Cummins
  • Feng Li
  • Jialin Jin
  • Xiaoping Fan
  • Sen Wang
  • Lingyun Shao
  • Shu Zhang
  • Shufang Meng
  • Jing Wu
  • Chanyi Lu
  • Lawrence B Blyn
  • Rangarajan Sampath
  • David J Ecker
  • Wenhong Zhang
  • Yi-Wei Tang
چکیده

We used multilocus PCR and electrospray ionization mass spectrometry (PCR/ESI-MS) to determine the genotype and drug resistance profiles for 96 Mycobacterium tuberculosis isolates circulating in regions of high and low tuberculosis (TB) endemicity in China. The dominant principal genetic group (PGG) circulating in China was PGG1, and drug-resistant gene mutations were more diversified in the region of low rather than high TB endemicity.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 49 7  شماره 

صفحات  -

تاریخ انتشار 2011